Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease.

Xiong, Wei

Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease. [electronic resource] - Nature neuroscience Feb 2014 - 232-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

1546-1726

10.1038/nn.3615 doi


6-Cyano-7-nitroquinoxaline-2,3-dione--pharmacology
Animals
Brain Stem--cytology
Disease Models, Animal
Excitatory Amino Acid Antagonists--pharmacology
Female
HEK293 Cells
Humans
In Vitro Techniques
Male
Membrane Potentials--drug effects
Mice
Mice, Inbred C57BL
Mice, Neurologic Mutants
Mutation--genetics
Neurons--drug effects
Presynaptic Terminals--drug effects
Receptors, Glycine--genetics
Sodium Channel Blockers--pharmacology
Spinal Cord--cytology
Stiff-Person Syndrome--genetics
Tetrodotoxin--pharmacology
Valine--analogs & derivatives