Improved mitochondrial function underlies the protective effect of pirfenidone against tubulointerstitial fibrosis in 5/6 nephrectomized rats.

Chen, Jun-Feng

Improved mitochondrial function underlies the protective effect of pirfenidone against tubulointerstitial fibrosis in 5/6 nephrectomized rats. [electronic resource] - PloS one 2013 - e83593 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0083593 doi


Animals
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Fibrosis--metabolism
Humans
Kidney Tubules, Proximal--metabolism
Male
Mitochondria--metabolism
Nephrectomy
Nephritis, Interstitial--metabolism
Pyridones--pharmacology
Rats
Rats, Sprague-Dawley
Renal Insufficiency, Chronic--metabolism