Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates.

Ferlazzo, Mélanie L

Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates. [electronic resource] - Molecular neurobiology Jun 2014 - 1200-11 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1559-1182

10.1007/s12035-013-8591-7 doi


Ataxia Telangiectasia Mutated Proteins--genetics
Cells, Cultured
DNA Breaks, Double-Stranded--drug effects
DNA Repair--drug effects
Diphosphonates--pharmacology
Female
Fibroblasts--drug effects
Humans
Huntingtin Protein
Huntington Disease--genetics
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Male
Mutation--drug effects
Nerve Tissue Proteins--genetics