Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer.
Polański, Radosław
Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Feb 2014 - 926-937 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-13-2270 doi
Adult
Aged
Aged, 80 and over
Animals
Antineoplastic Agents--pharmacology
Cell Death--drug effects
Cell Line, Tumor
Drug Resistance, Neoplasm
Female
Humans
Inhibitory Concentration 50
Kaplan-Meier Estimate
Lactic Acid--metabolism
Lung Neoplasms--drug therapy
Male
Mice
Mice, Inbred NOD
Mice, SCID
Middle Aged
Monocarboxylic Acid Transporters--antagonists & inhibitors
Multivariate Analysis
Muscle Proteins--metabolism
Pyrimidinones--pharmacology
Small Cell Lung Carcinoma--drug therapy
Symporters--antagonists & inhibitors
Thiophenes--pharmacology
Xenograft Model Antitumor Assays
Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Feb 2014 - 926-937 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-13-2270 doi
Adult
Aged
Aged, 80 and over
Animals
Antineoplastic Agents--pharmacology
Cell Death--drug effects
Cell Line, Tumor
Drug Resistance, Neoplasm
Female
Humans
Inhibitory Concentration 50
Kaplan-Meier Estimate
Lactic Acid--metabolism
Lung Neoplasms--drug therapy
Male
Mice
Mice, Inbred NOD
Mice, SCID
Middle Aged
Monocarboxylic Acid Transporters--antagonists & inhibitors
Multivariate Analysis
Muscle Proteins--metabolism
Pyrimidinones--pharmacology
Small Cell Lung Carcinoma--drug therapy
Symporters--antagonists & inhibitors
Thiophenes--pharmacology
Xenograft Model Antitumor Assays