Locking intracellular helices 2 and 3 together inactivates human P-glycoprotein.

Loo, Tip W

Locking intracellular helices 2 and 3 together inactivates human P-glycoprotein. [electronic resource] - The Journal of biological chemistry Jan 2014 - 229-36 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M113.527804 doi


ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1--chemistry
Adenosine Triphosphate--analogs & derivatives
Amino Acid Substitution
Cross-Linking Reagents--chemistry
HEK293 Cells
Humans
Mutation, Missense
Protein Folding
Protein Structure, Secondary
Protein Structure, Tertiary