Chemopreventive effects of an HDAC2-selective inhibitor on rat colon carcinogenesis and APCmin/+ mouse intestinal tumorigenesis.

Ravillah, Durgadevi

Chemopreventive effects of an HDAC2-selective inhibitor on rat colon carcinogenesis and APCmin/+ mouse intestinal tumorigenesis. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jan 2014 - 59-68 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1521-0103

10.1124/jpet.113.208645 doi


Adenomatous Polyposis Coli Protein--biosynthesis
Animals
Carcinogenesis--drug effects
Colonic Neoplasms--genetics
Disease Models, Animal
Female
HCT116 Cells
Histone Deacetylase 2--antagonists & inhibitors
Histone Deacetylase Inhibitors--therapeutic use
Humans
Intestinal Neoplasms--enzymology
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Phenylbutyrates--pharmacology
Rats
Rats, Inbred F344