Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome.

Bellin, Milena

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome. [electronic resource] - The EMBO journal Dec 2013 - 3161-75 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2075

10.1038/emboj.2013.240 doi


Action Potentials--genetics
Adult
Cells, Cultured
ERG1 Potassium Channel
Embryonic Stem Cells--physiology
Ether-A-Go-Go Potassium Channels--genetics
Female
Homeobox Protein Nkx-2.5
Homeodomain Proteins--genetics
Humans
Induced Pluripotent Stem Cells
Long QT Syndrome--genetics
Mutation
Myocytes, Cardiac--pathology
Patch-Clamp Techniques
Phenotype
Pluripotent Stem Cells--physiology
Protein Transport--genetics
Transcription Factors--genetics