Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice.

Song, Yinghua

Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice. [electronic resource] - Clinics (Sao Paulo, Brazil) Oct 2013 - 1350-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1980-5322

10.6061/clinics/2013(10)10 doi


Animals
Antibiotics, Antineoplastic
Anticarcinogenic Agents--pharmacology
Bleomycin
Carotenoids--pharmacology
Collagen Type I--blood
Collagen Type I, alpha 1 Chain
Collagen Type III--blood
Endothelin-1--blood
Enzyme-Linked Immunosorbent Assay
Female
Fibroblasts--drug effects
Fibrosis
Immunohistochemistry
Lung--drug effects
Matrix Metalloproteinase 1--blood
Mice
Mice, Inbred C3H
Real-Time Polymerase Chain Reaction
Scleroderma, Systemic--chemically induced
Skin--drug effects
Time Factors
Tissue Inhibitor of Metalloproteinase-1--blood
Vitamin A--analogs & derivatives