Repression of Smad7 mediated by DNMT1 determines hepatic stellate cell activation and liver fibrosis in rats.

Bian, Er-Bao

Repression of Smad7 mediated by DNMT1 determines hepatic stellate cell activation and liver fibrosis in rats. [electronic resource] - Toxicology letters Jan 2014 - 175-85 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-3169

10.1016/j.toxlet.2013.10.038 doi


Animals
DNA (Cytosine-5-)-Methyltransferase 1
DNA (Cytosine-5-)-Methyltransferases--physiology
Epigenesis, Genetic
Hepatic Stellate Cells--physiology
Liver Cirrhosis, Experimental--etiology
Male
Phosphorylation
Rats
Rats, Sprague-Dawley
Smad2 Protein--metabolism
Smad3 Protein--metabolism
Smad7 Protein--genetics
Transforming Growth Factor beta1--pharmacology
Wound Healing