Normal view MARC view ISBD view

Cannabinoid WIN-55,212-2 mesylate inhibits interleukin-1β induced matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase expression in human chondrocytes.

Dunn, S L

Cannabinoid WIN-55,212-2 mesylate inhibits interleukin-1β induced matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase expression in human chondrocytes. [electronic resource] - Osteoarthritis and cartilage Jan 2014 - 133-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

ISSN: 1522-9653

Standard No.: 10.1016/j.joca.2013.10.016 doi

Subjects--Topical Terms:
Alginates
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Benzoxazines--pharmacology
Cartilage, Articular--metabolism
Cell Death--drug effects
Cells, Cultured
Chondrocytes--drug effects
Drug Evaluation, Preclinical--methods
Gene Expression Regulation--drug effects
Glucuronic Acid
Hexuronic Acids
Humans
Interleukin-1beta--antagonists & inhibitors
Matrix Metalloproteinase 13--biosynthesis
Matrix Metalloproteinase 3--biosynthesis
Matrix Metalloproteinases--biosynthesis
Morpholines--pharmacology
Naphthalenes--pharmacology
Osteoarthritis, Knee--metabolism
Receptors, Cannabinoid--metabolism
Tissue Inhibitor of Metalloproteinase-1--biosynthesis
Tissue Inhibitor of Metalloproteinase-2--biosynthesis
Tissue Inhibitor of Metalloproteinases--biosynthesis