Liposomal-formulated curcumin [Lipocurc™] targeting HDAC (histone deacetylase) prevents apoptosis and improves motor deficits in Park 7 (DJ-1)-knockout rat model of Parkinson's disease: implications for epigenetics-based nanotechnology-driven drug platform.

Chiu, Simon

Liposomal-formulated curcumin [Lipocurc™] targeting HDAC (histone deacetylase) prevents apoptosis and improves motor deficits in Park 7 (DJ-1)-knockout rat model of Parkinson's disease: implications for epigenetics-based nanotechnology-driven drug platform. [electronic resource] - Journal of complementary & integrative medicine Nov 2013

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1553-3840

10.1515/jcim-2013-0020 doi


Animals
Animals, Genetically Modified
Apoptosis--drug effects
Curcumin--administration & dosage
Disease Models, Animal
Dopaminergic Neurons--drug effects
Exploratory Behavior--drug effects
Gene Knockout Techniques
Histone Deacetylase Inhibitors--administration & dosage
Histone Deacetylases--drug effects
Nootropic Agents--administration & dosage
Parkinson Disease--drug therapy
Psychomotor Disorders--drug therapy
Random Allocation
Rats