Benchmarking in vitro covalent binding burden as a tool to assess potential toxicity caused by nonspecific covalent binding of covalent drugs.
Dahal, Upendra P
Benchmarking in vitro covalent binding burden as a tool to assess potential toxicity caused by nonspecific covalent binding of covalent drugs. [electronic resource] - Chemical research in toxicology Nov 2013 - 1739-45 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-5010
10.1021/tx400301q doi
Adamantane--analogs & derivatives
Aspirin--chemistry
Carbon Radioisotopes--chemistry
Cells, Cultured
Drug-Related Side Effects and Adverse Reactions
Glutathione--chemistry
Half-Life
Hepatocytes--drug effects
Humans
Lactones--chemistry
Lysine--chemistry
Nitriles--chemistry
Orlistat
Pharmaceutical Preparations--chemistry
Pyrrolidines--chemistry
Tritium--chemistry
Vildagliptin
Benchmarking in vitro covalent binding burden as a tool to assess potential toxicity caused by nonspecific covalent binding of covalent drugs. [electronic resource] - Chemical research in toxicology Nov 2013 - 1739-45 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-5010
10.1021/tx400301q doi
Adamantane--analogs & derivatives
Aspirin--chemistry
Carbon Radioisotopes--chemistry
Cells, Cultured
Drug-Related Side Effects and Adverse Reactions
Glutathione--chemistry
Half-Life
Hepatocytes--drug effects
Humans
Lactones--chemistry
Lysine--chemistry
Nitriles--chemistry
Orlistat
Pharmaceutical Preparations--chemistry
Pyrrolidines--chemistry
Tritium--chemistry
Vildagliptin