A directional switch of integrin signalling and a new anti-thrombotic strategy.
Shen, Bo
A directional switch of integrin signalling and a new anti-thrombotic strategy. [electronic resource] - Nature Nov 2013 - 131-5 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1476-4687
10.1038/nature12613 doi
Amino Acid Motifs
Amino Acid Sequence
Animals
Antithrombins--adverse effects
Binding Sites
Bleeding Time
Cell Polarity
Cytoplasm--metabolism
GTP-Binding Protein alpha Subunits, G12-G13--metabolism
Hemorrhage--chemically induced
Humans
Integrin beta3--chemistry
Integrins--chemistry
Male
Mice
Mice, Inbred C57BL
Molecular Sequence Data
Platelet Glycoprotein GPIIb-IIIa Complex--metabolism
Protein Binding
Protein Structure, Tertiary
Signal Transduction--drug effects
Talin--metabolism
Thrombosis--drug therapy
A directional switch of integrin signalling and a new anti-thrombotic strategy. [electronic resource] - Nature Nov 2013 - 131-5 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1476-4687
10.1038/nature12613 doi
Amino Acid Motifs
Amino Acid Sequence
Animals
Antithrombins--adverse effects
Binding Sites
Bleeding Time
Cell Polarity
Cytoplasm--metabolism
GTP-Binding Protein alpha Subunits, G12-G13--metabolism
Hemorrhage--chemically induced
Humans
Integrin beta3--chemistry
Integrins--chemistry
Male
Mice
Mice, Inbred C57BL
Molecular Sequence Data
Platelet Glycoprotein GPIIb-IIIa Complex--metabolism
Protein Binding
Protein Structure, Tertiary
Signal Transduction--drug effects
Talin--metabolism
Thrombosis--drug therapy