Optimization of routine KRAS mutation PCR-based testing procedure for rational individualized first-line-targeted therapy selection in metastatic colorectal cancer.

Chretien, Anne-Sophie

Optimization of routine KRAS mutation PCR-based testing procedure for rational individualized first-line-targeted therapy selection in metastatic colorectal cancer. [electronic resource] - Cancer medicine Feb 2013 - 11-20 p. digital

Publication Type: Journal Article

2045-7634

10.1002/cam4.47 doi


Adult
Aged
Aged, 80 and over
Colorectal Neoplasms--drug therapy
DNA Mutational Analysis--methods
DNA, Neoplasm--genetics
Female
Humans
Male
Middle Aged
Molecular Targeted Therapy
Mutation
Neoplasm Metastasis
Nucleic Acid Denaturation
Patient Selection
Polymerase Chain Reaction--methods
Polymorphism, Restriction Fragment Length
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins p21(ras)
Sensitivity and Specificity
Young Adult
ras Proteins--genetics