Level of HER2 gene amplification predicts response and overall survival in HER2-positive advanced gastric cancer treated with trastuzumab.

Gomez-Martin, Carlos

Level of HER2 gene amplification predicts response and overall survival in HER2-positive advanced gastric cancer treated with trastuzumab. [electronic resource] - Journal of clinical oncology : official journal of the American Society of Clinical Oncology Dec 2013 - 4445-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1527-7755

10.1200/JCO.2013.48.9070 doi


Adult
Aged
Aged, 80 and over
Antibodies, Monoclonal, Humanized--therapeutic use
Antineoplastic Agents--therapeutic use
Centromere--genetics
Chromosomes, Human, Pair 17--genetics
Female
Gene Amplification
Gene Dosage
Humans
Immunohistochemistry
In Situ Hybridization
In Situ Hybridization, Fluorescence
Kaplan-Meier Estimate
Male
Middle Aged
Prognosis
Receptor, ErbB-2--genetics
Stomach Neoplasms--drug therapy
Survival Analysis
Trastuzumab
Treatment Outcome