Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells.

Lloyd, Mitchell M

Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells. [electronic resource] - Free radical biology & medicine Dec 2013 - 1352-1362 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-4596

10.1016/j.freeradbiomed.2013.10.007 doi


Amino Acid Chloromethyl Ketones--pharmacology
Apoptosis--drug effects
Apoptosis Inducing Factor--metabolism
Atherosclerosis--pathology
Caspase 3--metabolism
Caspase 7--metabolism
Caspase Inhibitors--pharmacology
Cell Line
Cell Survival--drug effects
Coronary Vessels--cytology
Cytochromes c--metabolism
Endodeoxyribonucleases--metabolism
Endothelial Cells--cytology
Glutathione--metabolism
Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)--antagonists & inhibitors
Humans
Hydrogen Peroxide
Hypochlorous Acid--chemistry
Mitochondrial Membranes
Necrosis--chemically induced
Oxidation-Reduction--drug effects
Permeability--drug effects
Peroxidase--metabolism
Sulfhydryl Compounds--chemistry
Thiocyanates--chemistry