Blocking the apolipoprotein E/amyloid β interaction in triple transgenic mice ameliorates Alzheimer's disease related amyloid β and tau pathology.
Liu, Shan
Blocking the apolipoprotein E/amyloid β interaction in triple transgenic mice ameliorates Alzheimer's disease related amyloid β and tau pathology. [electronic resource] - Journal of neurochemistry Feb 2014 - 577-91 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1471-4159
10.1111/jnc.12484 doi
Alzheimer Disease--drug therapy
Amino Acid Sequence
Amyloid beta-Peptides--antagonists & inhibitors
Amyloidosis--drug therapy
Animals
Apolipoproteins E--antagonists & inhibitors
Blotting, Western
Brain Chemistry--drug effects
Enzyme-Linked Immunosorbent Assay
Exploratory Behavior--physiology
Gliosis--pathology
Immunohistochemistry
Maze Learning--drug effects
Mice
Mice, Transgenic
Molecular Sequence Data
Motor Activity--physiology
Peptide Fragments--pharmacology
Postural Balance--drug effects
tau Proteins--metabolism
Blocking the apolipoprotein E/amyloid β interaction in triple transgenic mice ameliorates Alzheimer's disease related amyloid β and tau pathology. [electronic resource] - Journal of neurochemistry Feb 2014 - 577-91 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1471-4159
10.1111/jnc.12484 doi
Alzheimer Disease--drug therapy
Amino Acid Sequence
Amyloid beta-Peptides--antagonists & inhibitors
Amyloidosis--drug therapy
Animals
Apolipoproteins E--antagonists & inhibitors
Blotting, Western
Brain Chemistry--drug effects
Enzyme-Linked Immunosorbent Assay
Exploratory Behavior--physiology
Gliosis--pathology
Immunohistochemistry
Maze Learning--drug effects
Mice
Mice, Transgenic
Molecular Sequence Data
Motor Activity--physiology
Peptide Fragments--pharmacology
Postural Balance--drug effects
tau Proteins--metabolism