20(S)-protopanaxadiol triggers mitochondrial-mediated apoptosis in human lung adenocarcinoma A549 cells via inhibiting the PI3K/Akt signaling pathway.

Zhang, Yun-Long

20(S)-protopanaxadiol triggers mitochondrial-mediated apoptosis in human lung adenocarcinoma A549 cells via inhibiting the PI3K/Akt signaling pathway. [electronic resource] - The American journal of Chinese medicine 2013 - 1137-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1793-6853

10.1142/S0192415X13500778 doi


Adenocarcinoma--pathology
Apoptosis--drug effects
Caspases--metabolism
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Down-Regulation--drug effects
Humans
Lung Neoplasms--pathology
Membrane Potential, Mitochondrial--drug effects
Oncogene Protein v-akt--physiology
Panax
Phosphatidylinositol 3-Kinases--physiology
Phytotherapy
Sapogenins--pharmacology
Signal Transduction--genetics
Tumor Cells, Cultured