Improved efficacy of acylfulvene in colon cancer cells when combined with a nuclear excision repair inhibitor.

van Midwoud, Paul M

Improved efficacy of acylfulvene in colon cancer cells when combined with a nuclear excision repair inhibitor. [electronic resource] - Chemical research in toxicology Nov 2013 - 1674-82 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1520-5010

10.1021/tx400255f doi


Antineoplastic Agents, Alkylating--chemistry
Cell Survival--drug effects
Chromatography, High Pressure Liquid
Colonic Neoplasms--metabolism
DNA Adducts--analysis
DNA Repair--drug effects
DNA Repair Enzymes--antagonists & inhibitors
Drug Synergism
HT29 Cells
Humans
Sesquiterpenes--chemistry
Spectrometry, Mass, Electrospray Ionization
Spiro Compounds--chemistry
Staurosporine--analogs & derivatives