HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress.

Rouault-Pierre, Kevin

HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress. [electronic resource] - Cell stem cell Nov 2013 - 549-63 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1875-9777

10.1016/j.stem.2013.08.011 doi


Animals
Apoptosis--physiology
Basic Helix-Loop-Helix Transcription Factors--genetics
Cells, Cultured
Endoplasmic Reticulum Stress--physiology
Hematopoietic Stem Cells--cytology
Humans
Leukemia, Myeloid, Acute--genetics
Mice
Mitochondria--metabolism
Reactive Oxygen Species--metabolism