Effects of salt status and blockade of mineralocorticoid receptors on aldosterone-induced cardiac injury.

Hattori, Takuya

Effects of salt status and blockade of mineralocorticoid receptors on aldosterone-induced cardiac injury. [electronic resource] - Hypertension research : official journal of the Japanese Society of Hypertension Feb 2014 - 125-33 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1348-4214

10.1038/hr.2013.124 doi


Aldosterone
Animals
Blood Pressure--drug effects
Body Weight--physiology
Diet, Sodium-Restricted
Echocardiography
Endothelins--physiology
Fibrosis
Heart Diseases--chemically induced
Heart Function Tests
Hyperaldosteronism--physiopathology
Hypertension--diagnosis
Immunohistochemistry
Male
Mineralocorticoid Receptor Antagonists--pharmacology
Myocarditis--pathology
Myocytes, Cardiac--pathology
Nephrectomy
Oxidative Stress--physiology
Rats
Rats, Sprague-Dawley
Real-Time Polymerase Chain Reaction
Renin-Angiotensin System--drug effects
Sodium--metabolism
Superoxides--metabolism
Ventricular Function, Left--physiology