BMP4 is involved in the chemoresistance of myeloid leukemia cells through regulating autophagy-apoptosis balance.
Zhao, Xielan
BMP4 is involved in the chemoresistance of myeloid leukemia cells through regulating autophagy-apoptosis balance. [electronic resource] - Cancer investigation Oct 2013 - 555-62 p. digital
Publication Type: Journal Article
1532-4192
10.3109/07357907.2013.834925 doi
Animals
Antimetabolites, Antineoplastic--pharmacology
Apoptosis
Apoptosis Regulatory Proteins--biosynthesis
Autophagy
Autophagy-Related Protein 5
Beclin-1
Bone Morphogenetic Protein 4--genetics
CDC2 Protein Kinase--biosynthesis
Caspase 2--metabolism
Caspase 3--metabolism
Caspase 9--metabolism
Cell Line, Tumor
Cell Proliferation
Cyclin B1--biosynthesis
Cytarabine--pharmacology
Drug Resistance, Neoplasm
Enzyme Activation
Female
Humans
Leukemia, Myeloid--drug therapy
Membrane Proteins--biosynthesis
Mice
Mice, Nude
Microtubule-Associated Proteins--biosynthesis
Neoplasm Transplantation
RNA Interference
RNA, Small Interfering
Up-Regulation
Xenograft Model Antitumor Assays
BMP4 is involved in the chemoresistance of myeloid leukemia cells through regulating autophagy-apoptosis balance. [electronic resource] - Cancer investigation Oct 2013 - 555-62 p. digital
Publication Type: Journal Article
1532-4192
10.3109/07357907.2013.834925 doi
Animals
Antimetabolites, Antineoplastic--pharmacology
Apoptosis
Apoptosis Regulatory Proteins--biosynthesis
Autophagy
Autophagy-Related Protein 5
Beclin-1
Bone Morphogenetic Protein 4--genetics
CDC2 Protein Kinase--biosynthesis
Caspase 2--metabolism
Caspase 3--metabolism
Caspase 9--metabolism
Cell Line, Tumor
Cell Proliferation
Cyclin B1--biosynthesis
Cytarabine--pharmacology
Drug Resistance, Neoplasm
Enzyme Activation
Female
Humans
Leukemia, Myeloid--drug therapy
Membrane Proteins--biosynthesis
Mice
Mice, Nude
Microtubule-Associated Proteins--biosynthesis
Neoplasm Transplantation
RNA Interference
RNA, Small Interfering
Up-Regulation
Xenograft Model Antitumor Assays