Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.

Puri, Neelu

Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides. [electronic resource] - Cancer letters Feb 2014 - 14-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-7980

10.1016/j.canlet.2013.09.010 doi


Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--metabolism
Bronchi--pathology
Carcinoma, Non-Small-Cell Lung--genetics
Cell Line, Tumor
Cell Proliferation
Cellular Senescence
Cyclin-Dependent Kinase Inhibitor p21--metabolism
Cyclin-Dependent Kinase Inhibitor p27--metabolism
DNA Damage
Epithelial Cells--cytology
Gene Expression Regulation, Neoplastic
Genetic Predisposition to Disease
Humans
Inhibitor of Growth Protein 1
Intracellular Signaling Peptides and Proteins--metabolism
Male
Mice
Mice, Nude
Neoplasm Transplantation
Neovascularization, Pathologic
Nuclear Proteins--metabolism
Oligonucleotides--genetics
Signal Transduction
Telomere--ultrastructure
Tumor Suppressor Proteins--metabolism
Vascular Endothelial Growth Factor A--metabolism