Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target.

Rasanen, Kati

Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target. [electronic resource] - Molecular & cellular proteomics : MCP Dec 2013 - 3778-92 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1535-9484

10.1074/mcp.M113.029587 doi


Animals
Carcinoma, Squamous Cell--genetics
Cell Differentiation
Cell Line, Tumor
Cell Proliferation
Cell Transformation, Neoplastic--genetics
Clone Cells
Collagen--genetics
Epithelial-Mesenchymal Transition--genetics
Extracellular Matrix--genetics
Extracellular Signal-Regulated MAP Kinases--genetics
Gene Expression Regulation, Neoplastic
Head and Neck Neoplasms--genetics
Humans
Matrix Metalloproteinase 2--genetics
Mice
Molecular Sequence Annotation
NF-kappa B--genetics
Neoplasm Transplantation
Protein Interaction Mapping
Proto-Oncogene Proteins c-akt--genetics
RNA, Small Interfering--genetics
S100 Calcium-Binding Protein A4
S100 Proteins--antagonists & inhibitors
Signal Transduction
Squamous Cell Carcinoma of Head and Neck