Dexmedetomidine, an α-2a adrenergic agonist, promotes ischemic tolerance in a murine model of spinal cord ischemia-reperfusion.
Bell, Marshall T
Dexmedetomidine, an α-2a adrenergic agonist, promotes ischemic tolerance in a murine model of spinal cord ischemia-reperfusion. [electronic resource] - The Journal of thoracic and cardiovascular surgery Jan 2014 - 500-6 p. digital
Publication Type: Journal Article
1097-685X
10.1016/j.jtcvs.2013.07.043 doi
Adrenergic alpha-2 Receptor Agonists--pharmacology
Animals
Aorta, Thoracic--surgery
Brain-Derived Neurotrophic Factor--metabolism
CREB-Binding Protein--metabolism
Constriction
Dexmedetomidine--pharmacology
Disease Models, Animal
Male
Mice
Mice, Inbred C57BL
Neuroprotective Agents--pharmacology
Phosphorylation
Proto-Oncogene Proteins c-akt--metabolism
Proto-Oncogene Proteins c-bcl-2--metabolism
Receptors, Adrenergic, alpha-2--drug effects
Reperfusion Injury--metabolism
Signal Transduction--drug effects
Spinal Cord--drug effects
Spinal Cord Ischemia--metabolism
Time Factors
Dexmedetomidine, an α-2a adrenergic agonist, promotes ischemic tolerance in a murine model of spinal cord ischemia-reperfusion. [electronic resource] - The Journal of thoracic and cardiovascular surgery Jan 2014 - 500-6 p. digital
Publication Type: Journal Article
1097-685X
10.1016/j.jtcvs.2013.07.043 doi
Adrenergic alpha-2 Receptor Agonists--pharmacology
Animals
Aorta, Thoracic--surgery
Brain-Derived Neurotrophic Factor--metabolism
CREB-Binding Protein--metabolism
Constriction
Dexmedetomidine--pharmacology
Disease Models, Animal
Male
Mice
Mice, Inbred C57BL
Neuroprotective Agents--pharmacology
Phosphorylation
Proto-Oncogene Proteins c-akt--metabolism
Proto-Oncogene Proteins c-bcl-2--metabolism
Receptors, Adrenergic, alpha-2--drug effects
Reperfusion Injury--metabolism
Signal Transduction--drug effects
Spinal Cord--drug effects
Spinal Cord Ischemia--metabolism
Time Factors