New platinum(II) complexes conjugated at position 7α of 17β-acetyl-testosterone as new combi-molecules against prostate cancer: design, synthesis, structure-activity relationships and biological evaluation.
Fortin, Sébastien
New platinum(II) complexes conjugated at position 7α of 17β-acetyl-testosterone as new combi-molecules against prostate cancer: design, synthesis, structure-activity relationships and biological evaluation. [electronic resource] - European journal of medicinal chemistry Oct 2013 - 433-43 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1768-3254
10.1016/j.ejmech.2013.08.011 doi
Animals
Antineoplastic Agents--chemical synthesis
Biological Assay
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Chick Embryo
Drug Design
Humans
Inhibitory Concentration 50
Male
Models, Animal
Organometallic Compounds--chemical synthesis
Platinum--chemistry
Prostatic Neoplasms--drug therapy
Structure-Activity Relationship
Testosterone--analogs & derivatives
New platinum(II) complexes conjugated at position 7α of 17β-acetyl-testosterone as new combi-molecules against prostate cancer: design, synthesis, structure-activity relationships and biological evaluation. [electronic resource] - European journal of medicinal chemistry Oct 2013 - 433-43 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1768-3254
10.1016/j.ejmech.2013.08.011 doi
Animals
Antineoplastic Agents--chemical synthesis
Biological Assay
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Chick Embryo
Drug Design
Humans
Inhibitory Concentration 50
Male
Models, Animal
Organometallic Compounds--chemical synthesis
Platinum--chemistry
Prostatic Neoplasms--drug therapy
Structure-Activity Relationship
Testosterone--analogs & derivatives