Dehydroepiandrosterone sulfate mediates activation of transcription factors CREB and ATF-1 via a Gα11-coupled receptor in the spermatogenic cell line GC-2.

Shihan, Mazen

Dehydroepiandrosterone sulfate mediates activation of transcription factors CREB and ATF-1 via a Gα11-coupled receptor in the spermatogenic cell line GC-2. [electronic resource] - Biochimica et biophysica acta Dec 2013 - 3064-3075 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-3002

10.1016/j.bbamcr.2013.08.015 doi


Activating Transcription Factor 1--metabolism
Animals
Blotting, Western
Cell Line
Cyclic AMP Response Element-Binding Protein--metabolism
Dehydroepiandrosterone Sulfate--pharmacology
Enzyme Activation--drug effects
Extracellular Signal-Regulated MAP Kinases--metabolism
Fluorescent Antibody Technique
GTP-Binding Protein alpha Subunits, Gq-G11--metabolism
Gene Silencing--drug effects
Male
Mice
Phosphorylation--drug effects
RNA, Small Interfering--metabolism
Receptors, Androgen--metabolism
Receptors, G-Protein-Coupled--metabolism
Spermatozoa--drug effects
Steryl-Sulfatase--metabolism
src-Family Kinases--metabolism