β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapy.
Cannavo, Alessandro
β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapy. [electronic resource] - Circulation Oct 2013 - 1612-22 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1524-4539
10.1161/CIRCULATIONAHA.113.002659 doi
Animals
Cardiomegaly--physiopathology
Disease Models, Animal
Disease Progression
Down-Regulation--physiology
Genetic Therapy--methods
Green Fluorescent Proteins--genetics
HEK293 Cells
Heart Failure--physiopathology
Humans
Male
Mice
Mice, Inbred C57BL
Myoblasts, Cardiac--cytology
Myocardial Infarction--physiopathology
Rats
Rats, Inbred WKY
Receptor Cross-Talk--physiology
Receptors, Adrenergic, beta-1--genetics
Receptors, Lysosphingolipid--genetics
Sphingosine-1-Phosphate Receptors
β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapy. [electronic resource] - Circulation Oct 2013 - 1612-22 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1524-4539
10.1161/CIRCULATIONAHA.113.002659 doi
Animals
Cardiomegaly--physiopathology
Disease Models, Animal
Disease Progression
Down-Regulation--physiology
Genetic Therapy--methods
Green Fluorescent Proteins--genetics
HEK293 Cells
Heart Failure--physiopathology
Humans
Male
Mice
Mice, Inbred C57BL
Myoblasts, Cardiac--cytology
Myocardial Infarction--physiopathology
Rats
Rats, Inbred WKY
Receptor Cross-Talk--physiology
Receptors, Adrenergic, beta-1--genetics
Receptors, Lysosphingolipid--genetics
Sphingosine-1-Phosphate Receptors