Inhibition of coagulation and thrombin-induced platelet activities by a synthetic dodecapeptide modeled on the carboxy-terminus of hirudin.

Jakubowski, J A

Inhibition of coagulation and thrombin-induced platelet activities by a synthetic dodecapeptide modeled on the carboxy-terminus of hirudin. [electronic resource] - Blood Jan 1990 - 399-406 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

0006-4971


Amino Acid Sequence
Anticoagulants
Blood Coagulation--drug effects
Blood Platelets--drug effects
Heparin--pharmacology
Hirudins--pharmacology
Humans
In Vitro Techniques
Molecular Sequence Data
Oligopeptides--pharmacology
Partial Thromboplastin Time
Peptide Fragments
Platelet Aggregation--drug effects
Platelet Aggregation Inhibitors--pharmacology
Thrombin--pharmacology
Thrombocytopenia--etiology
Thromboxane A2--biosynthesis