Selective inhibition of caspases in skeletal muscle reverses the apoptotic synaptic degeneration in slow-channel myasthenic syndrome.

Zhu, Haipeng

Selective inhibition of caspases in skeletal muscle reverses the apoptotic synaptic degeneration in slow-channel myasthenic syndrome. [electronic resource] - Human molecular genetics Jan 2014 - 69-77 p. digital

Publication Type: Journal Article

1460-2083

10.1093/hmg/ddt397 doi


Animals
Apoptosis--genetics
Calpain--metabolism
Caspase 3--metabolism
Caspase 7--metabolism
Caspase 9--metabolism
Cyclin-Dependent Kinase 5--metabolism
DNA Damage
Disease Models, Animal
Extremities--physiopathology
Gene Expression Regulation
Humans
Inhibitor of Apoptosis Proteins--metabolism
Male
Mice
Mice, Transgenic
Microscopy, Electron
Motor Endplate--physiopathology
Muscle, Skeletal--metabolism
Myasthenic Syndromes, Congenital--enzymology