RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation.

Suzuki, Aae

RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation. [electronic resource] - PloS one 2013 - e69315 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1932-6203

10.1371/journal.pone.0069315 doi


Animals
Blood Platelets--enzymology
Cell Membrane--metabolism
Cell Size
Cytoskeleton--metabolism
Gene Deletion
Gene Targeting
Megakaryocytes--enzymology
Mice
Mutation--genetics
Platelet Membrane Glycoprotein IIb--metabolism
Ploidies
Rheology
Thrombocytopenia--pathology
Thrombopoiesis
rhoA GTP-Binding Protein--deficiency