Reassembly of nucleosomes at the MLH1 promoter initiates resilencing following decitabine exposure.

Hesson, Luke B

Reassembly of nucleosomes at the MLH1 promoter initiates resilencing following decitabine exposure. [electronic resource] - PLoS genetics 2013 - e1003636 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1553-7404

10.1371/journal.pgen.1003636 doi


Adaptor Proteins, Signal Transducing--genetics
Azacitidine--administration & dosage
Cell Line, Tumor
Chromatin Assembly and Disassembly--genetics
CpG Islands--genetics
DNA Methylation--drug effects
Decitabine
Drug Resistance, Neoplasm--drug effects
Gene Expression Regulation, Neoplastic--drug effects
Gene Silencing
Humans
MutL Protein Homolog 1
Nuclear Proteins--genetics
Nucleosomes--genetics
Promoter Regions, Genetic--drug effects