Synthesis, biological evaluation and molecular docking studies of pyrazole derivatives coupling with a thiourea moiety as novel CDKs inhibitors.
Sun, Jian
Synthesis, biological evaluation and molecular docking studies of pyrazole derivatives coupling with a thiourea moiety as novel CDKs inhibitors. [electronic resource] - European journal of medicinal chemistry Oct 2013 - 1-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1768-3254
10.1016/j.ejmech.2013.07.003 doi
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cell Proliferation--drug effects
Cyclin-Dependent Kinases--antagonists & inhibitors
Enzyme Activation--drug effects
Humans
Inhibitory Concentration 50
Molecular Docking Simulation
Molecular Structure
Protein Kinase Inhibitors--chemical synthesis
Pyrazoles--chemistry
Thiourea--chemistry
Synthesis, biological evaluation and molecular docking studies of pyrazole derivatives coupling with a thiourea moiety as novel CDKs inhibitors. [electronic resource] - European journal of medicinal chemistry Oct 2013 - 1-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1768-3254
10.1016/j.ejmech.2013.07.003 doi
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cell Proliferation--drug effects
Cyclin-Dependent Kinases--antagonists & inhibitors
Enzyme Activation--drug effects
Humans
Inhibitory Concentration 50
Molecular Docking Simulation
Molecular Structure
Protein Kinase Inhibitors--chemical synthesis
Pyrazoles--chemistry
Thiourea--chemistry