A novel bioactivity of andrographolide from Andrographis paniculata on cerebral ischemia/reperfusion-induced brain injury through induction of cerebral endothelial cell apoptosis.
Yen, Ting-Lin
A novel bioactivity of andrographolide from Andrographis paniculata on cerebral ischemia/reperfusion-induced brain injury through induction of cerebral endothelial cell apoptosis. [electronic resource] - Pharmaceutical biology Sep 2013 - 1150-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1744-5116
10.3109/13880209.2013.782051 doi
Andrographis--chemistry
Animals
Anti-Inflammatory Agents, Non-Steroidal--adverse effects
Apoptosis--drug effects
Blood-Brain Barrier--drug effects
Caspase 3--chemistry
Cell Survival--drug effects
Cells, Cultured
Cerebral Ventricles--blood supply
Diterpenes--adverse effects
Endothelium, Vascular--cytology
Enzyme Activation--drug effects
Infarction, Middle Cerebral Artery--physiopathology
Male
Mice
Plant Leaves--chemistry
Rats
Rats, Wistar
Reperfusion Injury--chemically induced
Resting Phase, Cell Cycle--drug effects
A novel bioactivity of andrographolide from Andrographis paniculata on cerebral ischemia/reperfusion-induced brain injury through induction of cerebral endothelial cell apoptosis. [electronic resource] - Pharmaceutical biology Sep 2013 - 1150-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1744-5116
10.3109/13880209.2013.782051 doi
Andrographis--chemistry
Animals
Anti-Inflammatory Agents, Non-Steroidal--adverse effects
Apoptosis--drug effects
Blood-Brain Barrier--drug effects
Caspase 3--chemistry
Cell Survival--drug effects
Cells, Cultured
Cerebral Ventricles--blood supply
Diterpenes--adverse effects
Endothelium, Vascular--cytology
Enzyme Activation--drug effects
Infarction, Middle Cerebral Artery--physiopathology
Male
Mice
Plant Leaves--chemistry
Rats
Rats, Wistar
Reperfusion Injury--chemically induced
Resting Phase, Cell Cycle--drug effects