Tetrandrine potentiates the hypoglycemic efficacy of berberine by inhibiting P-glycoprotein function.
Shan, Yong-Qiang
Tetrandrine potentiates the hypoglycemic efficacy of berberine by inhibiting P-glycoprotein function. [electronic resource] - Biological & pharmaceutical bulletin 2013 - 1562-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1347-5215
10.1248/bpb.b13-00272 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--antagonists & inhibitors
Animals
Area Under Curve
Benzylisoquinolines--pharmacology
Berberine--pharmacokinetics
Biotransformation
Blood Glucose--metabolism
Caco-2 Cells
Cytochrome P-450 CYP3A Inhibitors
Diabetes Mellitus--drug therapy
Dose-Response Relationship, Drug
Drug Interactions
Hep G2 Cells
Humans
Hypoglycemic Agents--pharmacokinetics
Intestinal Mucosa--metabolism
MCF-7 Cells
Mice
Mice, Inbred ICR
Phytotherapy
Plant Extracts--pharmacology
Rhodamine 123--metabolism
Stephania--chemistry
Tetrandrine potentiates the hypoglycemic efficacy of berberine by inhibiting P-glycoprotein function. [electronic resource] - Biological & pharmaceutical bulletin 2013 - 1562-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1347-5215
10.1248/bpb.b13-00272 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--antagonists & inhibitors
Animals
Area Under Curve
Benzylisoquinolines--pharmacology
Berberine--pharmacokinetics
Biotransformation
Blood Glucose--metabolism
Caco-2 Cells
Cytochrome P-450 CYP3A Inhibitors
Diabetes Mellitus--drug therapy
Dose-Response Relationship, Drug
Drug Interactions
Hep G2 Cells
Humans
Hypoglycemic Agents--pharmacokinetics
Intestinal Mucosa--metabolism
MCF-7 Cells
Mice
Mice, Inbred ICR
Phytotherapy
Plant Extracts--pharmacology
Rhodamine 123--metabolism
Stephania--chemistry