A mouse model of human hyperinsulinism produced by the E1506K mutation in the sulphonylurea receptor SUR1.

Shimomura, Kenju

A mouse model of human hyperinsulinism produced by the E1506K mutation in the sulphonylurea receptor SUR1. [electronic resource] - Diabetes Nov 2013 - 3797-806 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1939-327X

10.2337/db12-1611 doi


Aging--physiology
Animals
Blood Glucose--metabolism
Calcium--metabolism
Disease Models, Animal
Heterozygote
Homozygote
Humans
Hyperinsulinism--genetics
Insulin--metabolism
Insulin Secretion
Islets of Langerhans--physiopathology
KATP Channels--physiology
Mice
Potassium Channel Blockers--pharmacology
Sulfonylurea Receptors--genetics