AC-186, a selective nonsteroidal estrogen receptor β agonist, shows gender specific neuroprotection in a Parkinson's disease rat model.
McFarland, Krista
AC-186, a selective nonsteroidal estrogen receptor β agonist, shows gender specific neuroprotection in a Parkinson's disease rat model. [electronic resource] - ACS chemical neuroscience Sep 2013 - 1249-55 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1948-7193
10.1021/cn400132u doi
Animals
Corpus Striatum--chemistry
Cyclohexanes--chemistry
Cytokines--analysis
Drug Evaluation, Preclinical
Estradiol--therapeutic use
Estrogen Receptor beta--agonists
Exploratory Behavior--drug effects
Female
Male
Molecular Structure
Nerve Tissue Proteins--analysis
Neuroprotective Agents--chemistry
Ovariectomy
Oxidopamine--toxicity
Parkinsonian Disorders--chemically induced
Phenols--chemistry
Rats
Rats, Sprague-Dawley
Reflex, Startle--drug effects
Rotarod Performance Test
Sex Factors
Substantia Nigra--chemistry
Tyrosine 3-Monooxygenase--analysis
AC-186, a selective nonsteroidal estrogen receptor β agonist, shows gender specific neuroprotection in a Parkinson's disease rat model. [electronic resource] - ACS chemical neuroscience Sep 2013 - 1249-55 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1948-7193
10.1021/cn400132u doi
Animals
Corpus Striatum--chemistry
Cyclohexanes--chemistry
Cytokines--analysis
Drug Evaluation, Preclinical
Estradiol--therapeutic use
Estrogen Receptor beta--agonists
Exploratory Behavior--drug effects
Female
Male
Molecular Structure
Nerve Tissue Proteins--analysis
Neuroprotective Agents--chemistry
Ovariectomy
Oxidopamine--toxicity
Parkinsonian Disorders--chemically induced
Phenols--chemistry
Rats
Rats, Sprague-Dawley
Reflex, Startle--drug effects
Rotarod Performance Test
Sex Factors
Substantia Nigra--chemistry
Tyrosine 3-Monooxygenase--analysis