Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer.

Jain, Ajay

Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer. [electronic resource] - European journal of cancer (Oxford, England : 1990) Oct 2013 - 3344-52 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1879-0852

10.1016/j.ejca.2013.06.009 doi


Antibodies, Monoclonal--immunology
Antibody-Dependent Cell Cytotoxicity
Cell Line, Tumor
Colonic Neoplasms--genetics
ErbB Receptors--genetics
Genotype
HT29 Cells
Humans
Immunoglobulin Fc Fragments--immunology
Killer Cells, Natural--immunology
Polymorphism, Single Nucleotide
Protein Multimerization
Protein Structure, Tertiary