Carboxylated mesoporous carbon microparticles as new approach to improve the oral bioavailability of poorly water-soluble carvedilol.

Zhang, Yanzhuo

Carboxylated mesoporous carbon microparticles as new approach to improve the oral bioavailability of poorly water-soluble carvedilol. [electronic resource] - International journal of pharmaceutics Sep 2013 - 403-11 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1873-3476

10.1016/j.ijpharm.2013.07.009 doi


Administration, Oral
Adsorption
Animals
Biological Availability
Caco-2 Cells
Calorimetry, Differential Scanning
Carbazoles--administration & dosage
Carbon--chemistry
Carboxylic Acids--chemistry
Carvedilol
Cell Survival--drug effects
Chemistry, Pharmaceutical
Chromatography, High Pressure Liquid
Crystallography, X-Ray
Dogs
Drug Carriers
Humans
Male
Microscopy, Electron, Scanning
Microscopy, Electron, Transmission
Nanotechnology
Particle Size
Porosity
Powder Diffraction
Propanolamines--administration & dosage
Solubility
Solvents--chemistry
Surface Properties
Technology, Pharmaceutical--methods
Water--chemistry