Enhanced cell growth and tumorigenicity of rat glioma cells by stable expression of human CD133 through multiple molecular actions.

Fang, Kuan-Min

Enhanced cell growth and tumorigenicity of rat glioma cells by stable expression of human CD133 through multiple molecular actions. [electronic resource] - Glia Sep 2013 - 1402-17 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1098-1136

10.1002/glia.22521 doi


AC133 Antigen
Animals
Antigens, CD--genetics
Antineoplastic Agents--pharmacology
Arsenic Trioxide
Arsenicals--pharmacology
Basic Helix-Loop-Helix Transcription Factors--genetics
Brain Neoplasms--drug therapy
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cell Transformation, Neoplastic--genetics
Cerebral Cortex--pathology
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
Female
Formazans
GTPase-Activating Proteins--genetics
Gene Expression Regulation, Neoplastic--drug effects
Glioma--drug therapy
Glycoproteins--genetics
Homeodomain Proteins--genetics
Humans
Intercellular Signaling Peptides and Proteins--pharmacology
Lentivirus--genetics
Oncogene Protein v-akt--genetics
Oxides--pharmacology
Peptides--genetics
RNA, Messenger--metabolism
RNA, Small Interfering--genetics
Rats
Rats, Sprague-Dawley
Receptor, Notch1--genetics
Tetrazolium Salts
Time Factors
Transcription Factor HES-1
Transfection
Tumor Stem Cell Assay