β-Hydroxy-β-methylbutyrate (HMB) enhances the proliferation of satellite cells in fast muscles of aged rats during recovery from disuse atrophy.

Alway, Stephen E

β-Hydroxy-β-methylbutyrate (HMB) enhances the proliferation of satellite cells in fast muscles of aged rats during recovery from disuse atrophy. [electronic resource] - Experimental gerontology Sep 2013 - 973-84 p. digital

Publication Type: Journal Article

1873-6815

10.1016/j.exger.2013.06.005 doi


Aging--metabolism
Animals
Body Weight--drug effects
Cell Differentiation--drug effects
Cell Proliferation--drug effects
Dietary Supplements
Drug Evaluation, Preclinical
Eating--drug effects
Hindlimb Suspension
Isometric Contraction--drug effects
Male
Muscle, Skeletal--drug effects
Muscular Disorders, Atrophic--drug therapy
MyoD Protein--metabolism
Myogenin--metabolism
Nuclear Proteins--metabolism
Organ Size--drug effects
Paired Box Transcription Factors--metabolism
Rats
Rats, Inbred F344
Satellite Cells, Skeletal Muscle--drug effects
Signal Transduction--drug effects
Stem Cells--drug effects
TOR Serine-Threonine Kinases--metabolism
Valerates--pharmacology