A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells.
Miranda, Elena
A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. [electronic resource] - Journal of the American Chemical Society Jul 2013 - 10418-25 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-5126
10.1021/ja402993u doi
Aryl Hydrocarbon Receptor Nuclear Translocator--antagonists & inhibitors
Cell Line, Tumor
Dose-Response Relationship, Drug
Humans
Hypoxia
Hypoxia-Inducible Factor 1, alpha Subunit--antagonists & inhibitors
MCF-7 Cells
Peptides, Cyclic--chemical synthesis
Signal Transduction--drug effects
Structure-Activity Relationship
A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. [electronic resource] - Journal of the American Chemical Society Jul 2013 - 10418-25 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-5126
10.1021/ja402993u doi
Aryl Hydrocarbon Receptor Nuclear Translocator--antagonists & inhibitors
Cell Line, Tumor
Dose-Response Relationship, Drug
Humans
Hypoxia
Hypoxia-Inducible Factor 1, alpha Subunit--antagonists & inhibitors
MCF-7 Cells
Peptides, Cyclic--chemical synthesis
Signal Transduction--drug effects
Structure-Activity Relationship