A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons.

Zhao, Xiuli

A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons. [electronic resource] - Nature neuroscience Aug 2013 - 1024-31 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1546-1726

10.1038/nn.3438 doi


Animals
Ganglia, Spinal--metabolism
Gene Expression Regulation--genetics
Gene Silencing
Genetic Vectors
HEK293 Cells
Humans
Kv1.2 Potassium Channel--antagonists & inhibitors
Macaca fascicularis
Male
Mice
Mice, Inbred C57BL
Nerve Tissue Proteins--antagonists & inhibitors
Neuralgia--genetics
Neurons, Afferent--physiology
Peripheral Nerve Injuries
Promoter Regions, Genetic
RNA, Long Noncoding--antagonists & inhibitors
RNA, Messenger--biosynthesis
Rats
Rats, Sprague-Dawley
Spinal Cord--metabolism
Spinal Nerves--injuries
Trans-Activators--biosynthesis