Inactivation of Klf5 by zinc finger nuclease downregulates expression of pluripotent genes and attenuates colony formation in embryonic stem cells.

Long, Xilin

Inactivation of Klf5 by zinc finger nuclease downregulates expression of pluripotent genes and attenuates colony formation in embryonic stem cells. [electronic resource] - Molecular and cellular biochemistry Oct 2013 - 113-9 p. digital

Publication Type: Journal Article

1573-4919

10.1007/s11010-013-1724-5 doi


Animals
Cell Differentiation--genetics
Cell Shape--genetics
Colony-Forming Units Assay
Down-Regulation--genetics
Embryonic Stem Cells--cytology
Endonucleases--metabolism
Gene Expression Regulation, Developmental
Gene Targeting
Homeodomain Proteins--genetics
Kruppel-Like Transcription Factors--genetics
Mice
Nanog Homeobox Protein
Octamer Transcription Factor-3--genetics
Pluripotent Stem Cells--metabolism
SOXB1 Transcription Factors--genetics
Transfection
Zinc Fingers