Chronic low dose tumor necrosis factor-α (TNF) suppresses early bone accrual in young mice by inhibiting osteoblasts without affecting osteoclasts.

Gilbert, L C

Chronic low dose tumor necrosis factor-α (TNF) suppresses early bone accrual in young mice by inhibiting osteoblasts without affecting osteoclasts. [electronic resource] - Bone Sep 2013 - 174-83 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

1873-2763

10.1016/j.bone.2013.06.002 doi


Aging--drug effects
Animals
Biomarkers--metabolism
Bone and Bones--cytology
Cell Differentiation--drug effects
Cell Line
Cells, Cultured
Female
Male
Mesenchymal Stem Cells--cytology
Mice
Mice, Inbred C57BL
Mice, Transgenic
Osteoblasts--cytology
Osteoclasts--cytology
Tumor Necrosis Factor-alpha--administration & dosage
Wnt Signaling Pathway--drug effects