Treponema denticola major outer sheath protein impairs the cellular phosphoinositide balance that regulates neutrophil chemotaxis.

Visser, Michelle B

Treponema denticola major outer sheath protein impairs the cellular phosphoinositide balance that regulates neutrophil chemotaxis. [electronic resource] - PloS one 2013 - e66209 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0066209 doi


Animals
Bacterial Proteins--isolation & purification
CapZ Actin Capping Protein--genetics
Cell Polarity--drug effects
Chemotactic Factors--pharmacology
Chemotaxis, Leukocyte--drug effects
Gelsolin--genetics
Gene Expression Regulation--drug effects
Male
Mice
Mice, Inbred C57BL
N-Formylmethionine Leucyl-Phenylalanine--pharmacology
Neuropeptides--genetics
Neutrophils--drug effects
PTEN Phosphohydrolase--agonists
Phosphatidylinositol 3-Kinases--genetics
Phosphatidylinositol Phosphates--metabolism
Phosphoinositide-3 Kinase Inhibitors
Porins--isolation & purification
Primary Cell Culture
Proto-Oncogene Proteins c-akt--genetics
Signal Transduction
Treponema denticola--chemistry
rac1 GTP-Binding Protein--genetics