Characterization of a tumor-associated activating mutation of the p110β PI 3-kinase.

Dbouk, Hashem A

Characterization of a tumor-associated activating mutation of the p110β PI 3-kinase. [electronic resource] - PloS one 2013 - e63833 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0063833 doi


Amino Acid Sequence
Amino Acid Substitution
Animals
Blotting, Western
Breast Neoplasms--enzymology
Cell Membrane--metabolism
Cell Movement--genetics
Cell Proliferation
Cell Survival--genetics
Cell Transformation, Neoplastic--genetics
Class Ia Phosphatidylinositol 3-Kinase--genetics
Enzyme Activation--genetics
Female
HEK293 Cells
Humans
Liposomes--metabolism
Mice
Mutation
NIH 3T3 Cells
Phosphotransferases--metabolism
Protein Binding
Proto-Oncogene Proteins c-akt--metabolism
Ribosomal Protein S6 Kinases, 70-kDa--metabolism
Sequence Homology, Amino Acid
Sf9 Cells