Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients.

Robicsek, O

Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients. [electronic resource] - Molecular psychiatry Oct 2013 - 1067-76 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-5578

10.1038/mp.2013.67 doi


Antigens, Differentiation--biosynthesis
Cell Lineage
Cells, Cultured
Dopamine Agents--pharmacology
Ectoderm--cytology
Excitatory Amino Acid Agents--pharmacology
Gene Expression Regulation
Hair Follicle--pathology
Humans
Induced Pluripotent Stem Cells--metabolism
Keratinocytes--pathology
Membrane Potential, Mitochondrial
Mitochondria--metabolism
Models, Neurological
Nerve Tissue Proteins--biosynthesis
Neurogenesis
Neurons--drug effects
Oxygen Consumption
RNA, Messenger--biosynthesis
Schizophrenia, Paranoid--metabolism