Glycated albumin causes pancreatic β-cells dysfunction through autophagy dysfunction.

Song, Young Mi

Glycated albumin causes pancreatic β-cells dysfunction through autophagy dysfunction. [electronic resource] - Endocrinology Aug 2013 - 2626-39 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1945-7170

10.1210/en.2013-1031 doi


Animals
Apoptosis--drug effects
Autophagy--drug effects
Autophagy-Related Protein 5
Blotting, Western
Caspase 3--metabolism
Cell Line, Tumor
Cell Survival--drug effects
Glucose--pharmacology
Glycation End Products, Advanced
Green Fluorescent Proteins--genetics
Heat-Shock Proteins--genetics
Insulin--metabolism
Insulin-Secreting Cells--drug effects
Insulinoma--metabolism
Islets of Langerhans--drug effects
Male
Microscopy, Fluorescence
Microtubule-Associated Proteins--genetics
Nitric Oxide Synthase Type II--genetics
Proteins--genetics
RNA Interference
Rats
Rats, Sprague-Dawley
Reverse Transcriptase Polymerase Chain Reaction
Sequestosome-1 Protein
Serum Albumin--pharmacology
Transcription Factor RelA--metabolism
Glycated Serum Albumin