Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice.
Yang, Chen
Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jun 2013 - 9481-6 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1091-6490
10.1073/pnas.1307473110 doi
Animals
Blotting, Northern
Blotting, Western
Cross Protection
Dogs
Down-Regulation--genetics
Hemagglutinin Glycoproteins, Influenza Virus--metabolism
Influenza A Virus, H1N1 Subtype
Lethal Dose 50
Madin Darby Canine Kidney Cells
Male
Mice
Mice, Inbred BALB C
Neuraminidase--metabolism
Orthomyxoviridae Infections--immunology
Viral Vaccines--metabolism
Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jun 2013 - 9481-6 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1091-6490
10.1073/pnas.1307473110 doi
Animals
Blotting, Northern
Blotting, Western
Cross Protection
Dogs
Down-Regulation--genetics
Hemagglutinin Glycoproteins, Influenza Virus--metabolism
Influenza A Virus, H1N1 Subtype
Lethal Dose 50
Madin Darby Canine Kidney Cells
Male
Mice
Mice, Inbred BALB C
Neuraminidase--metabolism
Orthomyxoviridae Infections--immunology
Viral Vaccines--metabolism